|2011||apl Professor for Cell Biology|
|2006 to date||Vice Chair of the Dept. of Cell Biology, Center of Medical Research, Medical Faculty,
University of Rostock|
|2006||Venia legendi for animal physiology|
|2005||Habilitation, University of Rostock: Integrin receptors and their importance for cell adhesion and extracellular matrix-interaction and cell signalling – clinical aspects|
|1995||Dissertation, University of Rostock: thesis title: Flow cytometric characteristics of epithelial cells concerning integrin mediated interactions with extracellular matrix molecules, summa cum laude|
|1991||Dipl.-Ing. agr., University of Rostock: Principle investigations on hollow fiber coatings with collagen I|
|1980-91||Laboratory engineer, Center for Bioengineering, University of Rostock|
|1980||Laboratory engineer for veterinary medicine and diagnostics (equivalent to Dipl.-Ing. (FH)||
Her Topic of Materials' Days 2011:
Cell-Material Interacton on functionalized surfaces
The cell-material interaction on biomaterial surfaces (implants) can be influenced both by surface roughness (stochastic or regular geometry) and by chemical functionalization (physical plasma, protein immobilization), but unfortunately, there is little knowledge of their combinatory effects. In this concern we cooperate with the Leibniz Institute for Plasma Science and Technology e.V. (INP) in Greifswald.
Our focus of research is to analyse the cell behavior, in particular to understand signalling processes inside the cell, the organization of adhesion structures and, in consequence, the differentiation potential of cells induced by local physico-chemical characteristics of the biomaterial. Gaining insights into the complexity of cellular reactions at the biomaterial interface is a huge task for future research. For the design of biomaterial surfaces it is important to recognize changes of the single molecular components of cell adhesion at the material interface.